The right moisturizer can help you fight and prevent fine lines and wrinkles. Below, we’ve created a guide to the best moisturizers for wrinkles.

Our Recommendations

1. Rapid Wrinkle Repair Regenerating Cream

Rapid Wrinkle Repair Regenerating Cream

Neutrogena Moisturizer for Moisturization and Anti-Aging

Neutrogena Rapid Wrinkle Repair Regenerating Cream

This cream moisturizer combines the power of retinol and hyaluronic acid to fight the signs of aging while also plumping and moisturizing the skin.

Skin types: Normal, Dry and Combination
Best for: Moisturization and Anti-Aging
Tested on animals: Yes
How to use: After cleansing, apply the cream to your face, neck, and chest.
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This anti-aging moisturizer is a great way to add retinol to your routine, as the addition of moisturizing ingredients may help mitigate some of the irritation often associated with retinol. The cream contains retinol SA, which works to smooth lines and even skin tone. It also contains hyaluronic acid, which pulls moisture to the skin for healthy hydration levels.

Pros

  • Anti-aging
  • Fragrance-free
  • Non-greasy
  • Hydrating

Cons

  • May cause irritation

In addition to the hydrating benefits, hyaluronic acid has been shown to help minimize the appearance of fine lines and wrinkles, which makes this drugstore moisturizer even more effective for anti-aging. Even though the hydrating ingredients may mitigate the irritating effects of retinol, if you’re new to this skincare ingredient or have sensitive skin, you may want to start by using this cream every other day or every two days to see how your skin reacts.

Water, Pentaerythrityl Tetraethylhexanoate, Glycerin, Dimethicone, PPG 15 Stearyl Ether, Stearyl Alcohol, Cetearyl Alcohol, Butylene Glycol, Glyceryl Behenate, Ceteareth 20, Isohexadecane, Dimethicone Crosspolymer, Cyclopentasiloxane, Polyethylene, Sodium Polyacrylate, Phenoxyethanol, Caprylyl Glycol, Sodium Acryloyldimethyltaurate/VP Crosspolymer, Polyacrylamide, PTFE, C13-14 Isoparaf n, Chlorphenesin, Polysorbate 20, Hydrolyzed Myrtus Communis Leaf Extract, Retinol, BHT, Sodium Hyaluronate, Disodium EDTA, Sodium Hydroxide, Laureth-7, Ascorbic Acid

  1. National Center for Biotechnology Information. "Retinoids in the treatment of skin aging: An overview of clinical efficacy and safety"

    Accessed Nov. 8, 2021.
  2. National Center for Biotechnology Information. "Hyaluronic acid: A key molecule in skin aging"

    Accessed Nov. 8, 2021.

2. Redermic R Retinol Eye Cream

La Roche-Posay Redermic R Retinol Eye Cream

La Roche-Posay Moisturizer for Fine Lines and Wrinkles Around the Eyes

La Roche-Posay Redermic R Retinol Eye Cream

Lines around the eyes are a common complaint, and this eye cream is one of the best La Roche-Posay products for wrinkles in that area. This cream uses the power of retinol to help diminish fine lines and wrinkles.

Skin types: All Skin Types
Best for: Fine Lines and Wrinkles Around the Eyes
Tested on animals: Yes
How to use: Gently pat the eye cream around the entire eye area.
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The star ingredient in this eye cream is retinol, a well-studied skincare ingredient that has been shown to minimize the look of fine lines and wrinkles. It also contains caffeine, which helps diminish the look of dark circles.

Pros

  • Fragrance-free
  • Lightweight gel texture

Cons

  • Retinol may cause dryness or irritation

This eye cream is lightweight, and best suited for use at night.

Aqua / Water, Isocetyl Stearate, Glycerin, Octyldodecanol, Propylene Glycol, Pentylene Glycol, Dimethicone, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Cetearyl Alcohol, Dimethicone/Vinyl Dimethicone Crosspolymer, Caffein, Isohexadecane, Sodium Hyaluronate, Sodium Hydroxide, Retinol, Retinyl Linoleate, Adenosine, Ammonium Polyacryldimethyltauramide / Ammonium Polyacryloyldimethyl Taurate, Caprylyl Glycol, Citric Acid, Polysilicone-8, Polysorbate 80, Phenoxyethanol.

  1. National Center for Biotechnology Information. "Retinoids in the treatment of skin aging: An overview of clinical efficacy and safety"

    Accessed Aug. 20, 2021.

3. Redermic R Retinol Cream

La Roche-Posay Redermic R Retinol Cream

La Roche-Posay Moisturizer for Anti-Aging and Moisturization

La Roche-Posay Redermic R Retinol Cream

This cream combines retinol and lipo-hydroxy acid with moisturizing ingredients. These ingredients help even skin tone and texture and provide anti-aging benefits while keeping the skin moisturized.

Skin types: All Skin Types
Best for: Anti-Aging and Moisturization
Tested on animals: Yes
How to use: After cleansing, apply the cream all over the face, neck, and chest.
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This moisturizer contains retinol, an incredibly effective skincare ingredient that diminishes fine lines and wrinkles while also tackling sun spots and hyperpigmentation. It also contains lipo-hydroxy acid, which exfoliates, smoothes, and brightens. Sodium hyaluronate, glycerin, and other ingredients help soothe and moisturize the skin, which is excellent for also cutting down on irritation. This makes this cream a great choice for someone who is new to using retinol.

Pros

  • Lightweight
  • Oil-free
  • Dermatologist tested

Cons

  • Contains fragrance

Since this cream already contains retinol, you should not layer it on top of products with other potentially irritating ingredients (like another retinol serum or exfoliating serum).

Aqua / Water, Isostearyl Neopentanoate, Glycerin, Octyldodecanol, Propylene Glycol, Pentylene Glycol, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Cetearyl Alcohol, Glycine Soja Oil / Soybean Oil, Triethanolamine, Isohexadecane, Sodium Hyaluronate, Retinol, Retinyl Linoleate, Adenosine, Capryloyl Salicylic Acid, Caprylyl Glycol, Polysorbate 80, Phenoxyethanol, Parfum / Fragrance.

  1. National Center for Biotechnology Information. "The Use of Lipohydroxy Acid in Skin Care and Acne Treatment"

    Accessed Aug. 20, 2021.
  2. National Center for Biotechnology Information. "Retinoids in the treatment of skin aging: An overview of clinical efficacy and safety"

    Accessed Aug. 20, 2021.

4. Resist Intensive Repair Cream

Paula’s Choice Resist Intensive Repair Cream

Paula's Choice Moisturizer for Intense Moisturization and Anti-Aging Benefits

Paula’s Choice Resist Intensive Repair Cream

This ultra-rich face cream contains a concentrated blend of ingredients that restore, deeply hydrate, and fight the signs of aging, including a low concentration of retinol.

Skin types: Normal and Dry
Best for: Intense Moisturization and Anti-Aging Benefits
Tested on animals: No
How to use: After cleansing and applying serums and treatments, apply the moisturizer over your face, neck, and chest.
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This face cream contains a low concentration of retinol (0.01%), a skincare ingredient that is considered the gold-standard for fighting signs of aging, including fine lines and wrinkles. While the concentration is not super high, it is great for people who want to gently work retinol into their routine, but are worried about irritation from higher concentration treatments.

Pros

  • Fragrance-free
  • Intensely moisturizing
  • Anti-aging

Cons

  • Some reviewers note it has a greasy texture

In addition to the retinol, this cream contains hyaluronic acid, which locks in moisture and plumps the skin to reduce the appearance of fine lines. It also contains a blend of antioxidants that fight environmental aggressors to protect the skin.

Water (Aqua), Ethylhexyl Stearate (texture-enhancing), Simmondsia Chinensis (Jojoba) Seed Oil, Butylene Glycol, Glycerin, Caprylic/Capric Triglyceride, Petrolatum, Cetearyl Alcohol, Dimethicone, Dipentaerythrityl Hexacaprylate/Hexacaprate, Glyceryl Stearate, Tridecyl Trimellitate, PEG-100 Stearate, Phenyl Trimethicone, Retinol, Adenosine, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Palmitoyl Tripeptide-1, Ceramide NG, Sodium Hyaluronate, Magnesium Ascorbyl Phosphate, Niacinamide, Tocopherol, Lecithin, Linoleic Acid, Linolenic Acid, Retinyl Palmitate, Glycyrrhiza Glabra (Licorice) Root Extract, Camellia Oleifera (Green Tea) Leaf Extract, Citrullus Lanatus (Watermelon) Fruit Extract, Lens Esculenta (Lentil) Fruit Extract, Pyrus Malus (Apple) Fruit Extract, Glycine Soja (Soybean) Sterols, Tribehenin, PEG-10 Phytosterol, Magnesium Aluminum Silicate, Sodium PCA, Sodium Lactate, Pullulan, Xanthan Gum, Sodium Hydroxide, Neopentyl Glycol Dicaprylate/Dicaprate, Cetearyl Glucoside, Tridecyl Stearate, Behenyl Alcohol, Sclerotium Gum, Carbomer, C12-15 Alkyl Benzoate, Polysorbate 20, Disodium EDTA, Sorbic Acid, Phenoxyethanol, Chlorphenesin, Benzoic Acid

5. Resist Anti-Aging Eye Cream

Paula’s Choice Resist Anti-Aging Eye Cream

Paula's Choice Moisturizer for Reducing the Signs of Aging and Hydrating the Eye Area

Paula’s Choice Resist Anti-Aging Eye Cream

This balm-like eye cream contains a blend of ingredients that hydrate, reduce puffiness and dark circles, and minimize wrinkles.

Skin types: All Skin Types
Best for: Reducing the Signs of Aging and Hydrating the Eye Area
Tested on animals: No
How to use: Gently pat the eye cream around the entire eye area.
See on Amazon

This rich eye cream contains antioxidants and hydrating ingredients that are excellent for minimizing wrinkles around the eye area. These ingredients also help with other eye-related concerns, including puffiness, dark circles, and dry skin.

Pros

  • Fragrance-free
  • Rich texture

Cons

  • Texture may be too thick for daytime use

Hydrating and anti-aging ingredients in this eye cream include shea butter, glycerin, allantoin, and vitamin C.

Water (Aqua), Butyrospermum Parkii Butter (shea butter/emollient/antioxidant), Glycerin hydration/skin replenishing), Dimethicone (hydration), Sodium PCA (hydration/skin replenishing), Hydrogenated Polyisobutene (texture-enhancing), Ascorbyl Glucoside (vitamin C/antioxidant), Sodium Polyacrylate (texture-enhancing), Hydrogenated Lecithin (skin-restoring), Glucosyl Hesperidin (skin replenishing), Copper Gluconate (skin-restoring), Troxerutin (skin-restoring), Disodium Rutinyl Disulfate (skin-restoring), Resveratrol (antioxidant), Palmitoyl Tripeptide-38 (skin-restoring), Caprooyl Tetrapeptide-3 (skin-restoring), Glycyrrhiza Glabra Root Extract (licorice extract/skin-soothing), Phytic Acid (skin replenishing), Beta-Glucan (skin-soothing/antioxidant), Acetyl Glucosamine (skin replenishing), Tocopherol (vitamin E/antioxidant), Allantoin (skin-soothing), Adenosine (skin-restoring), Dextran (hydration/skin replenishing), Caprylic/Capric Triglyceride (emollient), Sea Whip Extract (skin-soothing), Arctostaphylos Uva Ursi Leaf Extract (bearberry extract/antioxidant), Salix Alba Bark Extract (willow bark extract/skin-soothing), Polyacrylate Crosspolymer-6 (texture-enhancing), Hydroxypropyl Cyclodextrin (texture-enhancing), Xanthan Gum (texture-enhancing), Cetearyl Alcohol (texture-enhancing), Maltodextrin (hydration), Benzyl Alcohol (preservative), Phenoxyethanol (preservative).

  1. National Center for Biotechnology Information. "The Roles of Vitamin C in Skin Health"

    Accessed Aug. 6, 2021.
  2. Sage Journals. "Safety Assessment of Glycerin as Used in Cosmetics"

    Accessed Aug. 6, 2021.
  3. National Center for Biotechnology Information. "Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils"

    Accessed Aug. 6, 2021.

FAQs

What is the best drugstore moisturizer for dry skin and wrinkles?

If you’re looking for an anti-aging drugstore moisturizer that is suitable for dry skin, try the Neutrogena Rapid Wrinkle Repair Regenerating Cream. This moisturizer contains retinol SA, which is an effective skincare ingredient for fighting wrinkles, as well as super hydrating ingredients like hyaluronic acid and glycerin.

What under eye moisturizer is best for removing wrinkles?

Two excellent eye creams that help minimize the appearance of wrinkles are the La Roche-Posay Redermic R Retinol Eye Cream and the Paula’s Choice Resist Anti-Aging Eye Cream. The La Roche-Posay eye cream contains retinol, which is one of the absolute best ingredients for smoothing wrinkles. The Paula’s Choice eye cream contains vitamin C, which helps fight signs of aging, as well as other ingredients that help with dry skin, puffiness, and dark circles.

How can I get rid of wrinkles on my face fast?

There’s no quick at-home fix for getting rid of wrinkles, but developing an effective anti-aging skincare routine (and being consistent with it) can help you minimize the appearance of wrinkles on your face over time, while also preventing new lines from forming. In addition to using a targeted anti-aging moisturizer, consider adding a retinol, a chemical exfoliant containing alpha hydroxy acids, and/or a vitamin C serum to your routine for the best results. There are other effective anti-aging ingredients you can look for in your skincare products, including peptides, niacinamide, and hyaluronic acid. For preventative purposes, it’s also essential that you wear sunscreen daily to protect against damaging UVA and UVB rays, which are one of the biggest culprits for causing premature signs of aging (including wrinkles).

The Bottom Line

If you’re looking to smooth out fine lines and wrinkles, a great moisturizer can help you achieve your skin goals. Consider adding one of our recommended moisturizers for wrinkles to your skincare routine for the best results.