If you’re looking to target specific skin concerns, a great serum might help. Below, we’ve created a guide to the best serums for sensitive skin.
Our Recommendations
1. Cicapair Tiger Grass Serum
Dr. Jart Serum for Soothing and minimizing redness
Dr. Jart Cicapair Tiger Grass Serum
This soothing serum is packed with ingredients that calm and minimize redness while strengthening the skin so that it can better defend itself against damage and irritation.
This is an excellent serum for those who need to calm and strengthen the skin while reducing redness. The formula is particularly great for sensitive and/or irritated skin. It is formulated with centella asiatica (AKA tiger grass) extract, which soothes inflammation and protects the skin. This gentle serum also contains Jartbiome, Dr. Jart’s microbiome complex that helps strengthen and balance while improving the skin’s ability to fight against irritation and damage. The company’s Cicabond blend (which contains proteins and minerals) repairs and rebuilds damaged skin.
Pros
- Lightweight
- Gentle
- Paraben-free
Cons
- Contains fragrant essential oils, which may irritate those with fragrance sensitivities
In addition to the ingredients mentioned above, this serum contains additional ingredients that calm, hydrate, and soothe redness, including niacinamide, glycerin, and panthenol.
Water/Eau, Dipropylene Glycol, Glycerin, Butylene Glycol, Propanediol, Eryngium Maritimum Callus Culture Filtrate, 1,2-Hexanediol, Niacinamide, Houttuynia Cordata Extract, Ilex Aquifolium (Holly) Leaf Extract, Achillea Millefolium Oil, Panthenol, Chondrus Crispus Extract, C12-14 Pareth-12, Saccharum Officinarum (Sugarcane) Extract/Extrait de canne à sucre, Streptococcus Thermophilus Ferment, Carbomer, Tromethamine, Madecassoside, Melia Azadirachta Leaf Extract, Xanthan Gum, Ethylhexylglycerin, Adenosine, Lavandula Angustifolia (Lavender) Oil, DNA, Disodium EDTA, Melia Azadirachta Flower Extract, Citrus Aurantium Bergamia (Bergamot) Fruit Oil, Asiaticoside, Dextrin, Theobroma Cacao (Cocoa) Extract, Centella Asiatica Leaf Extract, Hedera Helix (Ivy) Extract, Asiatic Acid, Madecassic Acid, Calcium Chloride, Centella Asiatica Extract, Magnesium Sulfate.
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National Center for Biotechnology Information. "Centella asiatica in cosmetology"
Accessed Jan. 11, 2022.
2. Vitamin C Serum
Mad Hippie Serum for Anti-aging and brightening
Mad Hippie Vitamin C Serum
This natural vitamin C serum contains sodium ascorbyl phosphate (a stable form of vitamin C) and other effective skincare ingredients to help brighten, hydrate, and provide anti-aging benefits.
This effective yet affordable vitamin C serum contains antioxidant-rich vitamin E and ferulic acid, which have been shown to increase the efficacy of vitamin C. It is also packed with additional ingredients that help hydrate, soften, and smooth the skin, including konjac root and hyaluronic acid.
Pros
- Natural
- Fragrance-free
- Vegan and cruelty-free
Cons
- Some reviewers noted it felt sticky on the skin
In addition to the ingredients mentioned above, this vegan and cruelty-free vitamin C serum contains chamomile, grapefruit, and clary sage, which provide antioxidant protection and calm the skin.
Water Deionized, Vitamin C (Sodium Ascorbyl Phosphate), Alkyl Benzoate, Vegetable Glycerin, Water, Glycerin, Sodium Levulinate, Sodium Anisate, Clary Sage (Salvia Sclarea), Grapefruit (Citrus Grandis), Hyaluronic acid, Amorphophallus Konjac Root Powder, Aloe Barbadensis Leaf, Vitamin E (Tocotrienol), Ferulic acid, Chamomile Flower Extract (Recutita Matricaria), Sodium Phytate, Xanthan Gum, Hydroxyethylcellulose
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National Center for Biotechnology. "Vitamin C in dermatology"
Accessed Nov. 11, 2021.
3. Power 10 Formula LI Effector with Licorice
It’s Skin Serum for Brightening and Evening Skin Tone
It’s Skin Power 10 Formula LI Effector with Licorice
This affordable serum contains a high concentration of licorice extract, which works to brighten and promote a more even skin tone.
This Korean serum is perfect for those looking to even out their skin tone. Licorice (glycyrrhiza uralensi) extract is known to help fade hyperpigmentation and melasma, improve skin texture, soothe the skin, and reduce redness.
Pros
- Affordable
- Gentle
- Fragrance-free
- Oil-free
Cons
- None
This daily serum can also be combined with other It’s Skin Power 10 serums to target specific skin concerns you’re looking to address.
Water, Glycyrrhiza, Glabra (Licorice) Root Extract, Butylene Glycol, Glycerin,Polyglutamic, Acid, Carbomer, Triethanolamine, Methylparaben, Chlorphenesin, Disodium EDTA
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National Center for Biotechnology Information. "Cosmeceuticals for Hyperpigmentation: What is Available?"
Accessed Nov. 10, 2021.
4. C E Ferulic with 15% L-Ascorbic Acid
SkinCeuticals Serum for Anti-aging and brightening
SkinCeuticals C E Ferulic with 15% L-Ascorbic Acid
This brightening and anti-aging vitamin C serum is often considered one of the best of the best. It helps improve signs of aging while fighting environmental aggressors.
This fragrance-free vitamin C serum contains a potent 15% concentration of l-ascorbic acid, a form of vitamin C that helps neutralize free radicals, defend against oxidative stress, and brighten and fight signs of aging. It is formulated with antioxidant-rich vitamin E and ferulic acid, which both further protect against environmental stressors. These ingredients have also been shown to increase the efficacy of vitamin C.
Pros
- Anti-aging
- Brightening
- Fragrance-free
Cons
- Expensive
- Some reviewers complain about the smell
This anti-aging serum remains effective for at least 72 hours after being absorbed into the skin. It also contains additional ingredients that help hydrate the skin, including glycerin and sodium hyaluronate.
Water, Ethoxydiglycol, L-Ascorbic Acid, Propylene Glycol, Glycerin, Laureth-23, Alpha Tocopherol, Phenoxyethanol, Triethanolamine, Ferulic Acid, Panthenol, Sodium Hyaluronate
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National Center for Biotechnology. "Vitamin C in dermatology"
Accessed Nov. 9, 2021.
5. Hydrium Centella Aqua Soothing Ampoule
COSRX Serum for Soothing and hydrating
COSRX Hydrium Centella Aqua Soothing Ampoule
This soothing and hydrating serum is packed with effective yet gentle ingredients that help soothe the skin. It is even suitable for calming current breakouts.
One of the key ingredients in this gentle serum is centella asiatica extract. This plant extract has been shown to effectively treat wounds and soothe inflammation in the skin. It also contains vitamin B5 (AKA panthenol), an anti-inflammatory ingredient that improves hydration and elasticity while soothing the skin.
Pros
- Lightweight and non-sticky
- Gentle
- Vegan and cruelty-free
- Fragrance-free
Cons
- The lighter hydration may not be hydrating enough for very dry skin
In addition to the ingredients mentioned above, this Korean serum contains madecassoside, which has antioxidant benefits, and allantoin, which soothes.
Water, Centella Asiatica Extract, Dipropylene Glycol, Glycerin, 1,2-Hexanediol, Betaine, Chondrus Crispus Extract, Saccharum Officinarum (Sugarcane) Extract, Pentylene Glycol, Octanediol, Ammonium Acryloyldimethyltaurate/VP Copolymer, Xanthan Gum, Ethylhexylglycerin, Allantoin, Madecassoside, Panthenol
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National Center for Biotechnology Information. "Centella asiatica in cosmetology"
Accessed Nov. 9, 2021. -
National Center for Biotechnology Information. "Skin moisturizing effects of panthenol-based formulations"
Accessed Nov. 9, 2021.
6. Moisture Renewal Oil Booster
Paula's Choice Serum for Extra Moisture
Paula’s Choice Moisture Renewal Oil Booster
This oil booster contains a blend of nourishing plant oils and renewing ceramides to help moisturize and revitalize dry skin.
This customer favorite booster contains nine non-fragrant, antioxidant-rich plant oils that alleviate dryness and calm the skin. It also contains ceramides, which further help restore the moisture barrier of the skin.
Pros
- Fragrance-free
- Non-irritating
Cons
- Some reviewers note it feels greasy on the skin
One of the key oils in this booster is jojoba oil, which is anti-inflammatory, can help restore the skin’s barrier, and has the ability to help fight the signs of aging. Another key ingredient in this blend is argan oil, a skin-softening oil that has been shown to improve elasticity and hydration.
Simmondsia Chinensis (Jojoba) Seed Oil (non-fragrant oil/skin-soothing/antioxidant/emollient), Carthamus Tinctorius (Safflower) Seed Oil (non-fragrant oil/skin-soothing/antioxidant/emollient), Prunus Armeniaca (Apricot) Kernel Oil (non-fragrant oil/skin-soothing/antioxidant/emollient), Helianthus Annuus (Sunflower) Seed Oil (non-fragrant oil/skin-soothing/antioxidant/emollient), Vaccinium Macrocarpon (Cranberry) Seed Oil (non-fragrant oil/skin-soothing/antioxidant/emollient), Argania Spinosa (Argan) Kernel Oil (non-fragrant oil/skin-soothing/antioxidant/emollient), Borago Officinalis (Borage) Seed Oil (non-fragrant oil/skin-soothing/antioxidant/emollient), Oenothera Biennis (Evening Primrose) Oil (non-fragrant oil/skin-soothing/antioxidant/emollient), Echium Plantagineum Seed Oil (non-fragrant oil/skin-soothing/antioxidant/emollient), Ceramide NS (hydration/skin replenishing), Cholesterol (hydration/skin replenishing)
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National Center for Biotechnology Information. "Skin hydration is significantly increased by a cream formulated to mimic the skin's own natural moisturizing systems"
Accessed Jul. 30, 2021. -
National Center for Biotechnology Information. "Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils"
Accessed Jul. 30, 2021.
7. Omega+ Complex Serum
Paula's Choice Serum for Strengthening the Skin’s Barrier and Hydration
Paula’s Choice Omega+ Complex Serum
This award-winning serum contains omega fatty acids and other replenishing ingredients that strengthen the skin’s barrier while reviving and hydrating the skin.
This is one of the best Paula’s Choice serums for all skin types, as it is gentle on the skin and keeps it healthy, hydrated, and strong. It locks in hydration and plumps to minimize the appearance of fine lines while also protecting the skin against environmental damage.
Pros
- Fragrance-free
- Gentle
Cons
- May not be suitable for acne-prone skin
This serum contains oils rich in omegas 3, 6, and 9, which strengthen and soothe the skin. It also contains ceramides to improve firmness and protect, as well as hyaluronic acid and shea butter to moisturize.
Water (Aqua), Glycerin (skin-replenishing ingredient), Diheptyl Succinate (emollient), Candelilla/Jojoba/Rice Bran Polyglyceryl-3 Esters (texture enhancer), Linum Usitatissimum (Linseed) Seed Oil (flax seed; non-fragrant omega -3, -6, and -9 plant oil), Linoleic Acid (skin-restoring omega-6 fatty acid), Linolenic Acid (skin-restoring omega-3 fatty acid), Passiflora Edulis Seed Oil (non-fragrant omega-6 plant oil, Salvia Hispanica (Chia) Seed Oil (non-fragrant omega-3 plant oil), Ceramide EOP (skin-restoring/replenishing), Ceramide EOS (skin-restoring/replenishing), Ceramide NP (skin-restoring/replenishing), Ceramide NS (skin-restoring/replenishing), Caprooyl Sphingosine (skin-restoring/replenishing), Olea Europaea (Olive) Oil Unsaponifiables (skin-smoothing antioxidant fatty acid), Caprooyl Phytosphingosine (skin-restoring), Sodium Hyaluronate (skin-replenishing/hydration), Cholesterol (skin-replenishing), Ceramide AP (skin-restoring/replenishing), Butyrospermum Parkii (Shea) Butter (antioxidant emollient), Tocopherol (vitamin E/antioxidant), Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer (texture enhancer/stabilizer), Prunus Domestica Seed Oil (non-fragrant antioxidant plant oil/omega-9 fatty acid), Lauryl Laurate (skin-softening opacifying agent), Glyceryl Behenate (emollient/emulsifier), Hydrogenated Lecithin (skin-restoring ingredient), Sodium Phytate (chelating agent), Trehalose (hydration), Isohexadecane (texture enhancer/solvent), Sodium Stearoyl Lactylate (emulsifier), Capryloyl Glycerin/Sebacic Acid Copolymer (film-forming agent), Xanthan Gum (texture enhancer), Cetyl Alcohol (hydration), Tetrahexyldecyl Ascorbate (vitamin C/antioxidant), Agar (binding agent), Glyceryl Stearate (emulsifier), Ceteareth-25 (solubilizer), Cetearyl Alcohol (hydration), Behenic Acid (opacifying agent), Glyceryl Rosinate (emollient), Citric Acid (pH adjuster), Benzyl Alcohol (preservative), Ethylhexylglycerin (preservative)
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Accessed Jul. 30, 2021.
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National Center for Biotechnology Information. "Skin hydration is significantly increased by a cream formulated to mimic the skin's own natural moisturizing systems"
Accessed Jul. 30, 2021.
8. Granactive Retinoid 2% Emulsion
The Ordinary Serum for Anti-Aging
The Ordinary Granactive Retinoid 2% Emulsion
This is a cult-favorite The Ordinary product, and one of the best for preventing and reducing the appearance of fine lines and wrinkles without the irritation often associated with traditional retinol.
The unique, next-generation retinoid actives in this serum makes it one of the best The Ordinary products for those who want to use a retinol but are worried about irritation. Retinoids (vitamin A derivatives) are well-known for preventing and reducing the appearance of fine lines, wrinkles, and other signs of aging.
Pros
- Oil-free
- Alcohol-free
- Fragrance-free
- Lightweight
- Vegan and cruelty-free
Cons
- Those with retinoid experience may prefer a stronger product
This product contains granactive retinoid, a complex of solubilized hydroxypinacolone retinoate (HPR). This form of retinoid offers anti-aging benefits without the irritation associated with retinol (which is also a vitamin A derivative). It also contains retinol that comes in a protective capsule to further prevent irritation, boost anti-aging benefits, and support the granactive retinoid.
Aqua (Water), Glycerin, Caprylic/Capric Triglyceride, Ethyl Linoleate, Propanediol, Dimethyl Isosorbide, Cetearyl Isononanoate, Bisabolol, Hydroxypinacolone Retinoate, Retinol, Tasmannia Lanceolata Fruit/Leaf Extract, Inulin Lauryl Carbamate, Glyceryl Stearate, Ceteareth-12, Ceteareth-20, Cetearyl Alcohol, Carrageenan, Xanthan Gum, Acacia Senegal Gum, Cetyl Palmitate, Sucrose Laurate, Polysorbate 20, Isoceteth-20, Rosmarinus Officinalis (Rosemary) Leaf Extract, Hydroxymethoxyphenyl Decanone, Behentrimonium Chloride, Trisodium Ethylenediamine Disuccinate, Disodium EDTA, Dehydroacetic Acid, Benzoic Acid, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin
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National Center for Biotechnology Information. "Retinoids in the treatment of skin aging: An overview of clinical efficacy and safety"
Accessed Aug. 11, 2021.
9. 100% Plant-Derived Squalane
The Ordinary Serum for Lightweight Hydration
The Ordinary 100% Plant-Derived Squalane
This squalane product looks, feels, and acts similarly to a light oil, but is actually oil-free. It is excellent for adding an extra boost of hydration to your skincare routine.
This squalane hydrator is one of the best The Ordinary products for acne-prone skin, because it is non-comedogenic. Even those who aren’t prone to breakouts will benefit from extra hydration this gentle and lightweight plant-based product provides.
Pros
- Oil-free
- Alcohol-free
- Vegan and cruelty-free
- Gentle
- Fragrance-free
Cons
- May not be hydrating enough for drier skin types
Squalene is naturally found in human sebum, which makes squalane (a derivative of squalene) well-tolerated by most. While this option is particularly great for those with normal to oily skin, all skin types can benefit from this gentle hydrator.
Squalane
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National Center for Biotechnology Information. "Moisturizers: The Slippery Road"
Accessed Aug. 13, 2021.
10. Hyaluronic Acid 2% + B5
The Ordinary Serum for Hydration
The Ordinary Hyaluronic Acid 2% + B5
This unique hyaluronic acid serum effectively attracts moisture to the skin to leave it feeling hydrated and plump.
This serum contains low-, medium-, and high-molecular weight hyaluronic acid, as well as a next-generation hyaluronic acid crosspolymer. This allows the serum to deliver much-needed hydration to all layers of the skin.
Pros
- Alcohol-free
- Vegan and cruelty-free
- Oil-free
- Hydrating
- Fragrance-free
Cons
- Some reviewers complain the serum feels sticky
In addition to the multiple forms of hyaluronic acid, this serum contains vitamin B5, which is anti-inflammatory and further helps hydrate the skin.
Aqua (Water), Sodium Hyaluronate, Pentylene Glycol, Propanediol, Sodium Hyaluronate Crosspolymer, Panthenol, Ahnfeltia Concinna Extract, Glycerin, Trisodium Ethylenediamine Disuccinate, Citric Acid, Isoceteth-20, Ethoxydiglycol, Ethylhexylglycerin, Hexylene Glycol, 1,2-Hexanediol, Phenoxyethanol, Caprylyl Glycol.
11. Redness Relief Repairing Serum
Paula's Choice Serum for Redness
Paula’s Choice Calm Redness Relief Repairing Serum
This calming, lightweight serum helps to reduce redness while also hydrating and fighting the signs of aging.
This is one of the best Paula’s Choice serums for soothing sensitive skin and reducing redness. It contains a potent blend of antioxidants and other skincare ingredients that hydrate and calm the skin. This serum is gentle on the skin, and even appropriate for skin prone to rosacea.
Pros
- Fragrance-free
- Gentle
- Lightweight
Cons
- May not be suitable for acne-prone skin
Some of the hydrating and soothing skincare ingredients in this serum include hyaluronic acid, sea whip extract, ceramides, licorice extract, and willow herb.
Water, Glycerin (skin replenishing), Hyaluronic Acid (hydration/skin replenishing), Beta-Glucan (skin-soothing/antioxidant), Sea Whip Extract (skin-soothing), Sodium Hyaluronate (hydration/skin replenishing), Ceramide NP (hydration/skin replenishing), Ceramide AP (hydration/skin replenishing), Ceramide EOP (hydration/skin replenishing), Cholesterol (skin replenishing), Glycyrrhiza Glabra Root Extract (licorice extract/skin-soothing), Epilobium Angustifolium Flower/Leaf/Stem Extract (willow herb/skin-soothing), Phytosphingosine (skin-renewing), Sodium Cocoyl Amino Acids (skin replenishing), Chrysanthemum Parthenium Flower Extract (feverfew extracts/antioxidant/skin-soothing), Glycine Soja Seed Extract (soybean extract/skin-soothing), Ubiquinone (antioxidant), Sodium Lauroyl Lactylate (texture-enhancing), Caprylic/Capric Triglyceride (skin replenishing/emollient), Magnesium Aspartate (emollient), Potassium Aspartate (emollient), Sarcosine (emollient), Xanthan Gum (texture-enhancing), Carbomer (texture-enhancing), Polysorbate 20 (texture-enhancing), PEG/PPG-14/4 Dimethicone (texture-enhancing), Disodium EDTA (stabilizer), Ethylhexylglycerin (preservative), Phenoxyethanol (preservative)
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Accessed Jul. 30, 2021.
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National Center for Biotechnology Information. "Skin hydration is significantly increased by a cream formulated to mimic the skin's own natural moisturizing systems"
Accessed Jul. 30, 2021.
12. Vitamin C Serum
TruSkin Serum for Brightening and Anti-Aging
TruSkin Vitamin C Serum
This gentle and affordable serum contains vitamin C, which brightens and fights signs of aging, as well as other soothing and hydrating skincare ingredients.
This vitamin C serum contains sodium ascorbyl phosphate, a stable form of vitamin C that helps brighten and provide anti-aging benefits. It also contains hyaluronic acid, which attracts moisture to the skin, and vitamin E, an antioxidant that protects against free radical damage to the skin.
Pros
- Affordable
- Fragrance-free
- Vegan and cruelty-free
Cons
- Some acne-prone reviewers noted that it broke them out
In addition to the ingredients mentioned above, this serum contains jojoba oil, which moisturizes, and witch hazel, which soothes.
Organic Deionized Herbal Infusion, Organic Aloe Barbadensis Leaf (Aloe), Sodium Ascorbyl Phosphate (Vitamin C), MSM, Botanical Hyaluronic Acid (Cassia Angustifolia Seed Polysaccharide), Hamamelis Virginiana (Witch Hazel), Vitamin E (d-alpha Tocopheryl Acetate), Carbomer, (2s)-2-Amino-5-guanidinopentanoic Acid, Organic Gotu Kola, Wildcrafted Horsetail (Equisetum Arvense), Wildcrafted Dandelion, Wildcrafted Geranium, Organic Jojoba Oil (Organic Simmondsia Chinensis), Phenoxyethanol, Ethyl Hexyl Glycerin.
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National Center for Biotechnology Information. "Sodium ascorbyl phosphate in topical microemulsions"
Accessed Aug. 31, 2021. -
National Center for Biotechnology Information. "Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils"
Accessed Aug. 31, 2021.
FAQs
Are serums bad for sensitive skin?
No, serums are not bad for sensitive skin. In fact, there are many excellent serums that target the skin issues that people with sensitive skin commonly deal with, such as redness and irritation. There are also serums specifically formulated with sensitive skin in mind that target a variety of skin concerns. If you have sensitive skin, it’s important to find the right serums for your skin type. You’ll also want to avoid serums that contain ingredients that may irritate your skin.
Is hyaluronic acid bad for sensitive skin?
Hyaluronic acid is generally well-tolerated by all skin types (including sensitive skin), but keep in mind that everyone’s skin is different. This is an excellent skincare ingredient for keeping the skin adequately hydrated, and it is found in a few of the serums mentioned above. You’ll find it listed as “hyaluronic acid” or “sodium hyaluronate” on ingredient labels. In general, when testing out a new product (whether it contains hyaluronic acid or not), it’s not a bad idea to first do a patch test to see how your skin reacts and to make sure you don’t experience any negative side effects. This is a particularly good idea for those with sensitive skin, since this skin type can be particularly reactive to new ingredients.
Which serum is best for dry and sensitive skin?
If you have sensitive skin that is dry, all of the options on this list will work for your skin type. If you’re really trying to boost hydration, an excellent option is the Paula’s Choice Moisture Renewal Oil Booster. This serum contains oils and ceramides that hydrate the skin while also supporting the skin’s barrier. The Paula’s Choice Omega+ Complex Serum is another great choice, as it contains omega-rich oils, shea butter, and hyaluronic acid to hydrate and strengthen the skin barrier. If you’re looking for a super simple serum that hydrates, the one-ingredient 100% Plant-Derived Squalane from The Ordinary is another amazing product.
The Bottom Line
People with sensitive skin can benefit from using a serum in their skincare routine. If you’re interested in using a serum, consider one of our recommended serums to maintain a healthy and happy complexion.