If you have dry skin, you can find plenty of excellent serums for your skin type at the drugstore. Below, we’ve put together a list of the best drugstore serums for dry skin.

Our Recommendations

1. Hyaluronic Acid Booster

Paula’s Choice Hyaluronic Acid Booster

Paula's Choice Serum for Hydration

Paula’s Choice Hyaluronic Acid Booster

This serum combines hyaluronic acid with ceramides and other deeply hydrating ingredients to give the skin an extra moisture boost.

Skin types: All Skin Types
Best for: Hydration
Tested on animals: No
How to use: Massage a pump of the serum into clean skin. Follow up with a moisturizer.
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Hyaluronic acid is a great skincare ingredient for all skin types, because it pulls moisture to the skin to help it maintain healthy hydration levels. The ceramides in this booster also help restore the moisture barrier and strengthen the skin.

Pros

  • Fragrance-free
  • Lightweight

Cons

  • May irritate sensitive skin

In addition to the hydrating benefits, hyaluronic acid has been shown to help minimize the appearance of fine lines and wrinkles, making this booster a great choice for those looking for anti-aging benefits.

Water (Aqua), Glycerin (hydration/skin replenishing), Sodium Hyaluronate (hydration/skin replenishing), Hyaluronic Acid (hydration/skin replenishing), Ceramide NP (hydration/skin replenishing), Ceramide AP (hydration/skin replenishing), Ceramide EOP (hydration/skin replenishing), Phytosphingosine (hydration/skin replenishing), Yeast Extract (skin replenishing), Adenosine (skin-restoring), Cholesterol (skin replenishing), Panthenol (skin replenishing), Silanetriol (hydration), Butylene Glycol (hydration), Sodium Lauroyl Lactylate (hydration), Carbomer (texture-enhancing), Xanthan Gum (texture-enhancing), Citric Acid, Sodium Hydroxide, Polysorbate 20 (texture-enhancing), Ethylhexylglycerin (preservative), Phenoxyethanol (preservative)

2. Moisture Renewal Oil Booster

Paula’s Choice Moisture Renewal Oil Booster

Paula's Choice Serum for Extra Moisture

Paula’s Choice Moisture Renewal Oil Booster

This oil booster contains a blend of nourishing plant oils and renewing ceramides to help moisturize and revitalize dry skin.

Skin types: All Skin Types
Best for: Extra Moisture
Tested on animals: No
How to use: Massage a few drops into clean skin. Follow up with a moisturizer.
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This customer favorite booster contains nine non-fragrant, antioxidant-rich plant oils that alleviate dryness and calm the skin. It also contains ceramides, which further help restore the moisture barrier of the skin.

Pros

  • Fragrance-free
  • Non-irritating

Cons

  • Some reviewers note it feels greasy on the skin

One of the key oils in this booster is jojoba oil, which is anti-inflammatory, can help restore the skin’s barrier, and has the ability to help fight the signs of aging. Another key ingredient in this blend is argan oil, a skin-softening oil that has been shown to improve elasticity and hydration.

Simmondsia Chinensis (Jojoba) Seed Oil (non-fragrant oil/skin-soothing/antioxidant/emollient), Carthamus Tinctorius (Safflower) Seed Oil (non-fragrant oil/skin-soothing/antioxidant/emollient), Prunus Armeniaca (Apricot) Kernel Oil (non-fragrant oil/skin-soothing/antioxidant/emollient), Helianthus Annuus (Sunflower) Seed Oil (non-fragrant oil/skin-soothing/antioxidant/emollient), Vaccinium Macrocarpon (Cranberry) Seed Oil (non-fragrant oil/skin-soothing/antioxidant/emollient), Argania Spinosa (Argan) Kernel Oil (non-fragrant oil/skin-soothing/antioxidant/emollient), Borago Officinalis (Borage) Seed Oil (non-fragrant oil/skin-soothing/antioxidant/emollient), Oenothera Biennis (Evening Primrose) Oil (non-fragrant oil/skin-soothing/antioxidant/emollient), Echium Plantagineum Seed Oil (non-fragrant oil/skin-soothing/antioxidant/emollient), Ceramide NS (hydration/skin replenishing), Cholesterol (hydration/skin replenishing)

  1. National Center for Biotechnology Information. "Skin hydration is significantly increased by a cream formulated to mimic the skin's own natural moisturizing systems"

    Accessed Jul. 30, 2021.
  2. National Center for Biotechnology Information. "Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils"

    Accessed Jul. 30, 2021.

3. Omega+ Complex Serum

Paula’s Choice Omega+ Complex Serum

Paula's Choice Serum for Strengthening the Skin’s Barrier and Hydration

Paula’s Choice Omega+ Complex Serum

This award-winning serum contains omega fatty acids and other replenishing ingredients that strengthen the skin’s barrier while reviving and hydrating the skin.

Skin types: All Skin Types
Best for: Strengthening the Skin’s Barrier and Hydration
Tested on animals: No
How to use: Massage a pump of the serum into clean skin. Follow up with a moisturizer.
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This is one of the best Paula’s Choice serums for all skin types, as it is gentle on the skin and keeps it healthy, hydrated, and strong. It locks in hydration and plumps to minimize the appearance of fine lines while also protecting the skin against environmental damage.

Pros

  • Fragrance-free
  • Gentle

Cons

  • May not be suitable for acne-prone skin

This serum contains oils rich in omegas 3, 6, and 9, which strengthen and soothe the skin. It also contains ceramides to improve firmness and protect, as well as hyaluronic acid and shea butter to moisturize.

Water (Aqua), Glycerin (skin-replenishing ingredient), Diheptyl Succinate (emollient), Candelilla/Jojoba/Rice Bran Polyglyceryl-3 Esters (texture enhancer), Linum Usitatissimum (Linseed) Seed Oil (flax seed; non-fragrant omega -3, -6, and -9 plant oil), Linoleic Acid (skin-restoring omega-6 fatty acid), Linolenic Acid (skin-restoring omega-3 fatty acid), Passiflora Edulis Seed Oil (non-fragrant omega-6 plant oil, Salvia Hispanica (Chia) Seed Oil (non-fragrant omega-3 plant oil), Ceramide EOP (skin-restoring/replenishing), Ceramide EOS (skin-restoring/replenishing), Ceramide NP (skin-restoring/replenishing), Ceramide NS (skin-restoring/replenishing), Caprooyl Sphingosine (skin-restoring/replenishing), Olea Europaea (Olive) Oil Unsaponifiables (skin-smoothing antioxidant fatty acid), Caprooyl Phytosphingosine (skin-restoring), Sodium Hyaluronate (skin-replenishing/hydration), Cholesterol (skin-replenishing), Ceramide AP (skin-restoring/replenishing), Butyrospermum Parkii (Shea) Butter (antioxidant emollient), Tocopherol (vitamin E/antioxidant), Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer (texture enhancer/stabilizer), Prunus Domestica Seed Oil (non-fragrant antioxidant plant oil/omega-9 fatty acid), Lauryl Laurate (skin-softening opacifying agent), Glyceryl Behenate (emollient/emulsifier), Hydrogenated Lecithin (skin-restoring ingredient), Sodium Phytate (chelating agent), Trehalose (hydration), Isohexadecane (texture enhancer/solvent), Sodium Stearoyl Lactylate (emulsifier), Capryloyl Glycerin/Sebacic Acid Copolymer (film-forming agent), Xanthan Gum (texture enhancer), Cetyl Alcohol (hydration), Tetrahexyldecyl Ascorbate (vitamin C/antioxidant), Agar (binding agent), Glyceryl Stearate (emulsifier), Ceteareth-25 (solubilizer), Cetearyl Alcohol (hydration), Behenic Acid (opacifying agent), Glyceryl Rosinate (emollient), Citric Acid (pH adjuster), Benzyl Alcohol (preservative), Ethylhexylglycerin (preservative)

4. Azelaic Acid Suspension 10%

The Ordinary Azelaic Acid Suspension 10%

The Ordinary Serum for Fighting Acne and Evening Skin Tone

The Ordinary Azelaic Acid Suspension 10%

This product from The Ordinary hosts an impressive variety of benefits. Azelaic acid is a brightening skincare ingredient known for minimizing acne, lightening hyperpigmentation, and reducing redness.

Skin types: All Skin Types
Best for: Fighting Acne and Evening Skin Tone
Tested on animals: No
How to use: After cleansing, apply the product to the face, neck, and chest. Follow up with a moisturizer.
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This product contains a 10% concentration of azelaic acid, a gentle exfoliator that has antibacterial, antioxidant, and anti-inflammatory properties. The lightweight gel-cream helps to improve and brighten skin tone, as well as unclog pores and reduce blemishes for clear, smooth skin.

Pros

  • Oil-free
  • Fragrance-free
  • Alcohol-free
  • Vegan and cruelty-free

Cons

  • Some reviewers note that this product can be drying

In addition to its ability to fight acne, azelaic acid is often used to treat rosacea to promote a more even skin tone.

Aqua (Water), Isodecyl Neopentanoate, Dimethicone, Azelaic Acid, Dimethicone/Bis-Isobutyl PPG-20 Crosspolymer, Dimethyl Isosorbide, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polysilicone-11, Isohexadecane, Tocopherol, Trisodium Ethylenediamine Disuccinate, Isoceteth-20, Polysorbate 60, Triethanolamine, Ethoxydiglycol, Phenoxyethanol, Chlorphenesin.

  1. National Center for Biotechnology Information. "Azelaic acid"

    Accessed Aug. 11, 2021.

5. 100% Plant-Derived Squalane

The Ordinary 100% Plant-Derived Squalane

The Ordinary Serum for Lightweight Hydration

The Ordinary 100% Plant-Derived Squalane

This squalane product looks, feels, and acts similarly to a light oil, but is actually oil-free. It is excellent for adding an extra boost of hydration to your skincare routine.

Skin types: All Skin Types
Best for: Lightweight Hydration
Tested on animals: No
How to use: After cleansing and applying serums, gently massage a few drops into the face, neck, and chest. Follow up with a moisturizer. This may also be used on top of a moisturizer to seal in hydration.
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This squalane hydrator is one of the best The Ordinary products for acne-prone skin, because it is non-comedogenic. Even those who aren’t prone to breakouts will benefit from extra hydration this gentle and lightweight plant-based product provides.

Pros

  • Oil-free
  • Alcohol-free
  • Vegan and cruelty-free
  • Gentle
  • Fragrance-free

Cons

  • May not be hydrating enough for drier skin types

Squalene is naturally found in human sebum, which makes squalane (a derivative of squalene) well-tolerated by most. While this option is particularly great for those with normal to oily skin, all skin types can benefit from this gentle hydrator.

Squalane

  1. National Center for Biotechnology Information. "Moisturizers: The Slippery Road"

    Accessed Aug. 13, 2021.

6. Hyalu B5 Pure Hyaluronic Acid Serum

La Roche-Posay Hyalu B5 Pure Hyaluronic Acid Serum

La Roche-Posay Serum for Hydration

La Roche-Posay Hyalu B5 Pure Hyaluronic Acid Serum

This serum combines pure hyaluronic acid with other hydrating ingredients that replenish the skin’s moisture barrier.

Skin types: All Skin Types
Best for: Hydration
Tested on animals: Yes
How to use: Dispense three to four drops of the serum into your hands, and gently massage into the skin. This serum can be used morning and night.
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Hyaluronic acid pulls moisture to the skin to help it maintain healthy hydration levels. This serum also contains vitamin B5 (panthenol), which acts as both a humectant (meaning it binds to and holds water in the skin) and an emollient (soothing and sealing water in the skin). Additionally, madecassoside works to further repair the skin.

Pros

  • Hydrating
  • Oil-free
  • Non-comedogenic
  • Dermatologist tested

Cons

  • Contains fragrance

In addition to the hydrating benefits, hyaluronic acid has been shown to help minimize the appearance of fine lines and wrinkles, making this serum a great choice for those also looking for anti-aging benefits.

Aqua / Water, Glycerin, Alcohol Denat., Propylene Glycol, Panthenol, Pentylene Glycol, Dimethicone, Peg-6 Caprylic/Capric Glycerides, Ppg-6-Decyltetradeceth-30, Glyceryl Isostearate, Madecassoside, Sodium Hyaluronate, Ammonium Polyacryloyldimethyl Taurate, Disodium Edta, Hydrolyzed Hyaluronic Acid, Caprylyl Glycol, Citric Acid, Xanathan Gum, Butylene Glycol, Tocopherol, Phenoxyethanol, Parfum / Fragrance

7. Hyaluronic Acid 2% + B5

Hyaluronic Acid 2% + B5

The Ordinary Serum for Hydration

The Ordinary Hyaluronic Acid 2% + B5

This unique hyaluronic acid serum effectively attracts moisture to the skin to leave it feeling hydrated and plump.

Skin types: All Skin Types
Best for: Hydration
Tested on animals: No
How to use: After cleansing, massage a few drops of the serum into the skin. Follow up with a moisturizer.
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This serum contains low-, medium-, and high-molecular weight hyaluronic acid, as well as a next-generation hyaluronic acid crosspolymer. This allows the serum to deliver much-needed hydration to all layers of the skin.

Pros

  • Alcohol-free
  • Vegan and cruelty-free
  • Oil-free
  • Hydrating
  • Fragrance-free

Cons

  • Some reviewers complain the serum feels sticky

In addition to the multiple forms of hyaluronic acid, this serum contains vitamin B5, which is anti-inflammatory and further helps hydrate the skin.

Aqua (Water), Sodium Hyaluronate, Pentylene Glycol, Propanediol, Sodium Hyaluronate Crosspolymer, Panthenol, Ahnfeltia Concinna Extract, Glycerin, Trisodium Ethylenediamine Disuccinate, Citric Acid, Isoceteth-20, Ethoxydiglycol, Ethylhexylglycerin, Hexylene Glycol, 1,2-Hexanediol, Phenoxyethanol, Caprylyl Glycol.

8. Redness Relief Repairing Serum

Paula’s Choice Calm Redness Relief Repairing Serum

Paula's Choice Serum for Redness

Paula’s Choice Calm Redness Relief Repairing Serum

This calming, lightweight serum helps to reduce redness while also hydrating and fighting the signs of aging.

Skin types: All Skin Types
Best for: Redness
Tested on animals: No
How to use: After cleansing, apply the booster to the face. Follow up with a moisturizer.
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This is one of the best Paula’s Choice serums for soothing sensitive skin and reducing redness. It contains a potent blend of antioxidants and other skincare ingredients that hydrate and calm the skin. This serum is gentle on the skin, and even appropriate for skin prone to rosacea.

Pros

  • Fragrance-free
  • Gentle
  • Lightweight

Cons

  • May not be suitable for acne-prone skin

Some of the hydrating and soothing skincare ingredients in this serum include hyaluronic acid, sea whip extract, ceramides, licorice extract, and willow herb.

Water, Glycerin (skin replenishing), Hyaluronic Acid (hydration/skin replenishing), Beta-Glucan (skin-soothing/antioxidant), Sea Whip Extract (skin-soothing), Sodium Hyaluronate (hydration/skin replenishing), Ceramide NP (hydration/skin replenishing), Ceramide AP (hydration/skin replenishing), Ceramide EOP (hydration/skin replenishing), Cholesterol (skin replenishing), Glycyrrhiza Glabra Root Extract (licorice extract/skin-soothing), Epilobium Angustifolium Flower/Leaf/Stem Extract (willow herb/skin-soothing), Phytosphingosine (skin-renewing), Sodium Cocoyl Amino Acids (skin replenishing), Chrysanthemum Parthenium Flower Extract (feverfew extracts/antioxidant/skin-soothing), Glycine Soja Seed Extract (soybean extract/skin-soothing), Ubiquinone (antioxidant), Sodium Lauroyl Lactylate (texture-enhancing), Caprylic/Capric Triglyceride (skin replenishing/emollient), Magnesium Aspartate (emollient), Potassium Aspartate (emollient), Sarcosine (emollient), Xanthan Gum (texture-enhancing), Carbomer (texture-enhancing), Polysorbate 20 (texture-enhancing), PEG/PPG-14/4 Dimethicone (texture-enhancing), Disodium EDTA (stabilizer), Ethylhexylglycerin (preservative), Phenoxyethanol (preservative)

9. 10% Azelaic Acid Booster

Paula’s Choice 10% Azelaic Acid Booster

Paula's Choice Serum for Evening Tone and Texture

Paula’s Choice 10% Azelaic Acid Booster

This booster combines azelaic acid with other brightening ingredients that work together to fade post-acne marks, minimize blemishes, brighten, and even out tone and texture.

Skin types: All Skin Types
Best for: Evening Tone and Texture
Tested on animals: No
How to use: After cleansing, apply the booster to affected areas or all over the skin. Follow up with a moisturizer.
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This is a great multi-purpose serum to have on hand. If you have hyperpigmentation, this is a particularly excellent product for you, as azelaic acid has been shown to help fade dark marks. It’s also great for smoothing the skin for a more even texture.

Pros

  • Fragrance-free
  • Oil-free
  • Lightweight

Cons

  • May irritate more sensitive skin types

This booster contains salicylic acid, a chemical exfoliator that further minimizes the appearance of blemishes and evens out skin texture and tone. It also contains licorice root, which calms redness and brightens.

Water (Aqua), Azelaic Acid (skin-brightening/tone-improving), C12-15 Alkyl Benzoate (emollient), Caprylic/Capric Triglyceride (skin-replenishing), Methyl Glucose Sesquistearate (emollient), Glycerin (skin-replenishing), Cetearyl Alcohol (texture enhancer), Glyceryl Stearate (texture enhancer), Dimethicone (hydration/texture enhancer), Salicylic Acid (exfoliant), Adenosine (skin-restoring), Glycyrrhiza Glabra (Licorice) Root Extract (skin-soothing), Boerhavia Diffusa Root Extract (skin-soothing), Allantoin (skin-soothing), Bisabolol (skin-soothing), Cyclopentasiloxane (texture enhancer), Xanthan Gum (stabilizer), Sclerotium Gum (stabilizer), Propanediol (hydration), Butylene Glycol (hydration), Phenoxyethanol (preservative)

  1. National Center for Biotechnology Information. "Postinflammatory Hyperpigmentation"

    Accessed Jul. 30, 2021.
  2. National Center for Biotechnology Information. "Over-the-counter Acne Treatments"

    Accessed Jul. 30, 2021.

FAQs

How do I choose a serum?

If you’re picking out a serum to add to your skincare routine, you’ll need to take into consideration your skin type, as well as any specific skin issues you’d like to address. From there, you can find a serum that contains ingredients that target your skin concerns and that is formulated for your skin type. For example, if you have dry skin and are looking for a serum that can help minimize redness, you’ll want to look for a product for your skin type that helps with that concern (like the Paula’s Choice Calm Redness Relief Repairing Serum).

Do serums hydrate the skin?

Some serums are formulated with ingredients that hydrate the skin. For example, many of the serums mentioned above contain hyaluronic acid, a skincare ingredient that attracts moisture to the skin to help with hydration. If you’re looking for a serum to help with hydration, be sure to seek out a product specifically formulated for hydration. Look for ingredients that are known for hydration, like hyaluronic acid and glycerin.

Do I need both a serum and a moisturizer?

Everyone should be using a moisturizer everyday, and this is particularly important for those with dry skin. Serums, on the other hand, aren’t necessarily essential in a skincare routine. However, they are great tools to give your skin a concentrated boost of specific skincare ingredients that target certain issues you may wish to address. If you choose to add a serum to your routine, apply it first (after cleansing). Follow up with a moisturizer, and then sunscreen during the day.

The Bottom Line

You can find a variety of excellent serums at the drugstore, and there are options for all skin types and skin concerns. If you have dry skin, consider adding one (or more) of the serums mentioned above to your routine to address any skin issues you may have.